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Voluntary transparency for performing high-quality, non-targeted mass spectrometry-based metabolomics analyses of plasma samples

Universitair Medisch Centrum Groningen (UMCG) · Onderhandeling zonder bekendmaking · 1 lots · 364418
Type
Services
85148000
Estimated value
Not published
To deadline
Ongoing
Knock-outs
n/a
exclusion grounds
Award basis
Best price-quality ratio
Assess manuallyconfidence low

This procurement was an underlaid, closed procedure for a complete service package regarding metabolomics (non-targeting) via Metabolon, with an emphasis on high-quality, technically robust mass spectrometry of plasma within the Lifelines cohort. The contract was intended for UMCG, published under TenderNed 364418 on January 21, 2025, and entails the required expertise, certifications, and library capabilities that only Metabolon can provide.

Services · Onderhandeling zonder bekendmaking · European procedure

European
Contracting authority
Universitair Medisch Centrum Groningen (UMCG)
Contract type
Services
Onderhandeling zonder bekendmaking
Estimated value
Estimate not published
Submission deadline
Ongoing
Scope
European
European procedure
Lots
1
1 lots
Main CPV code
85148000
Location
Netherlands
CharacteristicsCPV 85ServicesEU tender

01What is being requested

This procurement was an underlaid, closed procedure for a complete service package regarding metabolomics (non-targeting) via Metabolon, with an emphasis on high-quality, technically robust mass spectrometry of plasma within the Lifelines cohort. The contract was intended for UMCG, published under TenderNed 364418 on January 21, 2025, and entails the required expertise, certifications, and library capabilities that only Metabolon can provide.

This concerns the execution by Metabolon of high-quality, non-targeted mass spectrometry-based metabolomics analyses of plasma samples from the population-based Lifelines cohort, with the aim of identifying metabolic disturbances in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) that can be utilized for mechanistic, diagnostic, and therapeutic insights. After extensive market research, it has emerged that Metabolon is the only party capable of meeting specific requirements for the execution, namely: 1. Analysis: Metabolon analyzes each sample four times with different UHPLC settin

85148000Services
1Voluntary transparency for performing high-quality, non-targeted mass spectrometry-based metabolomics analyses of plasma samples—

02Exclusion grounds

Exclusion grounds — consult the ESPD
  • No specific exclusion grounds were extracted. In a European tender, the mandatory and discretionary grounds of art. 2.86/2.87 of the Dutch Procurement Act almost always apply — check the European Single Procurement Document (ESPD).

03Value in context

Estimate not published

The contracting authority did not publish an estimated value — common for a large share of contracts. The EU threshold for diensten is € 221.000, for reference.

04Likely competitors

#Likely bidderFitWins
1Stichting Streeklaboratorium voor de Volksgezondheid KennemerlandUnknown775×
21st LAB ConsortiumUnknown755×
3Sanquin Diagnostiek B.V.SME734×
4Gezondheidsdienst voor Dieren B.V.SME724×
5Stichting Gelre ZiekenhuizenUnknown724×
6Microvida CVUnknown724×

05Legal themes that may be relevant here

06Frequently asked questions

What is the purpose of the metabolomics analyses of the plasma samples?
The purpose is to perform high-quality, non-targeted mass spectrometry-based metabolomics analyses of plasma samples from the Lifelines cohort to identify metabolic disturbances in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) for mechanistic, diagnostic, and therapeutic insights.
What technical requirements must the analysis meet regarding sample processing?
The analysis requires that each sample is analyzed four times with different UHPLC settings. This enables non-targeted metabolomics of different molecules, which is essential due to differences in, for example, the polarity of molecules.
What role does the metabolite library play in this assignment?
The assignment utilizes a library of top tier 1 metabolites for the widest possible identification of metabolites from the raw data, which increases the accuracy of the identification.
What requirements are set for the certification and quality of the execution?
There is a requirement that the executing party has accredited methods for analyses in human plasma and meets the specific quality criteria established by the partners in the consortium.
Why was a non-targeted analysis approach chosen?
Because there are no a priori hypotheses regarding the pathogenesis of ME/CFS, a non-targeted approach is necessary to prevent relevant metabolic pathways from being missed during the research.

Automatically compiled from the official tender data and documents.

07Estimated value versus the market

p25
€ 962K
median
€ 16 mln
p75
€ 108 mln
deze opdracht

Gegunde waarden in CPV 85 · diensten n=1531